After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.
Kate is a young woman who has a habit of making bad decisions, and her last date with disaster occurs after she accepts work as Santa's elf for a department store. However, after she meets Tom there, her life takes a new turn.
After getting dumped for the 11th time in a row, Frankie discovers that she has a "loser in love" gene, which predisposes her to chronic failure and rejection for the rest of her life. She decides to embark on a quest to change her romantic future.