When a young boy dogsits Clyde, a criminal canine trying to go straight, he ends up facing down the school bully, catching a criminal, and learning valuable lessons about life from his new best friend.
A growth hormone experiment gets out of hand, when the the resulting giant man-eating rats escape, reaking havoc on the unsuspecting campus. Much blood-letting follows.
Jerry Lewis plays an Ohio optometrist who has a six-year old daughter with epilepsy. He fights to get the FDA to approve a drug (at that time only available in England) for use in the U.S.