In 1930s Argentina, dim-witted Rufino and Jacinto are hired as tough guys ("guapos") by political boss Malatesta to intimidate his opponents, rig elections, etc. However, the two men change allegiances when they meet the lovely Mercedes and La Mendocina, victims of Malatesta and his gang.
Alberto and Jorge are employees of a pharmacy. One day, by mistake, they give a client a bottle of poison in exchange for a medication that she had to start ingesting 48 hours later. Realizing this, they decide to go out and look for her with the only data they have: her first name, her striking clothing, and that she was driving an imported motorcycle. So they launch into a crazy race against time touring the fashionable places of the Buenos Aires night, helped by a woman who claims to know the mysterious girl on the motorcycle.
Alberto, Jorge, Ricardo and Tristan are employees of a shoe store, all are married and share the friendship also between their wives. The 4 friends, faithful to the rogue style of Buenos Aires, go out of their way to have love affairs with the beautiful customers of the shoe store, and for that purpose one day they decide to rent, secretly, an apartment to use as a "bulín". The problems begin from then on, as everyone wants to be the first to release it and then, successively, take turns for their adventures. As is to be expected, it does not take long for the first entanglements to appear, while their wives seem to begin to suspect the adventures of these four typical Buenos Aires chantas.