In the corridors of a Caracas hospital, two very dissimilar beings meet by chance one night. Coming from very different worlds, anxiety is the only thing they have in common. One of them is Antonieta Sanchez, a single mother who has made ends meet for herself and her son, Odulio, by washing clothes and ironing. She knows she has lost her son a long time ago: Odulio is a young criminal. The night he was shot, Antonieta's life changed forever. The other is Benigno Robles, an assistant district attorney who, as a young law student, devoted his career with hope and deeply rooted ideals of justice. When Elisa, his only daughter, is hit by a stray bullet, Benigno will never be the same. But this encounter between Antonieta and Benigno, seemingly coincidental, is not: there is a secret that will eventually come to light
In the early 1800s, Prussian geographer Alexander Von Humboldt and French botanist Aimé Bonpland launch an expedition to explore the Amazon region, including the Orinoco River, from Venezuela to the border of Portuguese Brazil.
In César Miguel Rondón's adaptation, a different origin story is presented. The fisherman Ismael (Félix Loreto) is unfaithful to his wife Cayita (Ana Karina) with a witch, Carmelina (Ileana Aloma). She swears revenge when she sees Ismael return to Cayita's arms and casts a curse that will cause the fisherman's death, setting his house on fire. Faced with the tragic event, Cayita, frightened, screams and begs the townspeople for help to save her son, who was inside the house when the fire started. Cayita's son dies alongside Ismael. It is then that she, crazed with grief, cries out for her son for eternity.