As the war between the vampires and the Lycans rages on, Selene, a former member of the Death Dealers (an elite vampire special forces unit that hunts werewolves), and Michael, the werewolf hybrid, work together in an effort to unlock the secrets of their respective bloodlines.
In 2035, where robots are commonplace and abide by the three laws of robotics, a technophobic cop investigates an apparent suicide. Suspecting that a robot may be responsible for the death, his investigation leads him to believe that humanity may be in danger.