Barbara Rand is blinded when she leaps through a window to escape an assailant. Her sister, Natalie, reluctantly abandons her fiancé, Ned Gardiner, and marries Oliver Landis, who can provide the money needed for Barbara's operation. Unaware that Oliver was Barbara's attacker, Natalie blames his business partner, Howard Pollard, who was with Barbara on the night she was injured. Natalie holds Howard at gunpoint, but when her husband arrives, he promises to deal with the villain making sure Howard falls to his death. Upon Barbara’s release from the hospital, Oliver tries to blind her once. Natalie threatens him with a pistol, but Oliver wrests it away from her. He then realizes that he can no longer hide his guilt from Natalie or the police and shoots himself. Barbara has been avenged, and Natalie is free to marry Ned.
Neglected by her workaholic husband Jack, Eileen Spencer begins an affair with novelist Carter Ballantyne. Their planned elopement is halted when Eileen learns that Jack has lost both his money and his eyesight, and she feels compelled to return to care for him. With her friend Dolly Page, Eileen cheats at cards amassing a fortune to send Jack to France for treatment. Carter reappears, threatening to expose her unless she submits to him. Intending merely to reason with Carter, Eileen gives him a key to her apartment, but Jack returns home unexpectedly and finds him there. At her birthday dinner, Eileen, in anticipation of Carter's plan to expose her publicly, confesses her guilt, whereas her husband and her friends forgive her.
John Howland travels to the frozen North to build a branch of the Hudson Bay Railroad. There he meets and falls in love with Meleese Thoreau who warns him that her three bloodthirsty brothers, Max, Pierre and François, have sworn vengeance against a man named John Howland, the son of a man who killed their mother, and that torture and death await him along the route to his station.