In New York City, bright but naive New Englander Anne Welles becomes a secretary at a theatrical law firm, where she falls in love with attorney Lyon Burke. Anne befriends up-and-coming singer Neely O'Hara, whose dynamic talent threatens aging star Helen Lawson and beautiful but talentless actress Jennifer North. The women experience success and failure in love and work, leading to heartbreak, addiction and tragedy.
Betty Bryant is an ambitious newspaper reporter in love with Dan Barton, a member of a big-city Emergency Squad who are trained to deal with riots, cave-in, explosions, fires and other emergencies where lives are at stake. Slade Wiley, an unscrupulous tunnel builder, finds that his low bid on the Newford Tunnel project is causing him to lose a lot of money, and has underworld leader Nick Burton set off blasts to frighten the stockholders into selling their shares at a low price so he can buy up the stock. Betty is investigating the deal when Wiley and Burton take her on a "tour trip" to the tunnel.
J.B. Ball, a rich financier, gets fed up with his free-spending family. He takes his wife's just-bought (very expensive) sable coat and throws it out the window, it lands on poor hard-working girl Mary Smith. But it isn't so easy to just give away something so valuable, as he soon learns.
The small-town prudes of Lynnfield are up in arms over 'The Sinner,' a sexy best-seller. They little suspect that author 'Caroline Adams' is really Theodora Lynn, scion of the town's leading family. Michael Grant, devil-may-care book jacket illustrator, penetrates Theodora's incognito and sets out to 'free her' from Lynnfield against her will. But Michael has a secret too, and gets a taste of his own medicine.
Charlie Mason and Rusty Fleming are star reporters on a Chicago tabloid who are romantically involved as well. Although skilled in ferreting out great stories, they often behave in an unprofessional and immature manner. After their shenanigans cause their frustrated city editor to resign, the publisher promotes Charlie to the job, a decision based on the premise that only a slacker would be able crack down on other shirkers and underachievers. His pomposity soon alienates most of his co-workers and causes Rusty to move to New York. Charlie resigns and along with gangster friend Smiles Benson tries to win Rusty back before she marries a stuffy society author.
Suspected crime boss Nate Girard beats a murder rap, and newspaper photog Kent Murdock is on the story. Girard and lawyer Redfield throw a party for the news men where Murdock romances a mystery woman who confronted Girard in front of him, but Murdock's fiancée Hester shows up. After they return to his apartment, have a fight, and she leaves, the mystery woman slips in and begs for his help. Police Inspector Bacon and the cops show up, looking for the mystery woman; Murdock hides her. Murdock goes with the cops to discuss the murder the woman is suspected of. Bacon explains (in flashback) how some photogs were setting up a shot with Girard and Redfield. When the flashbulbs popped, Redfield keeled over dead and the woman, Meg Archer, fled while the newsmen ran out to phone their papers. The newsmen (who were rounded up later as thoroly as possible) are taken into police custody, except for Murdock (who wasn't at the scene), who is given a cap on the sly by rival McGoogin. Altho ...