A biologist from London goes to Amazonia to study the local flora. There she meets three other scientists from different nationalities and backgrounds. They advise her not to go near the Autana, a mountain regarded sacred by the local tribes, without a guide. She will do exactly the contrary.
El Cholo, a Peruvian taxi driver, flees from justice in his country and comes to Venezuela in search for a better future. After running into a gang of con-men who leave him penniless, he meets a peculiar group of Latin Americans who work for a gangster known as The Russian as hitmen. El Cholo is quickly trapped in a world of blood and ambition that makes him realize the true cost of life and death.