After breaking up with her dreamboat, Marta finds love with an artist. But life throws a few twists into the mix for the ailing woman and her friends.
Carter, an art conservator, arrives in Italy to restore a fresco in an old church. He discovers that the strange locals are hiding something and a mystery relating to a nearby lake that legend says was created by a meteor.
An ancient urn is found in a cemetery outside Rome. Once opened, it triggers a series of violent incidents: robberies, rapes and murders increase dramatically, while several mysterious, evil-looking young women coming from all over the world are gathering in the city. All these events are caused by the return of Mater Lacrimarum, the last of three powerful witches who have been spreading terror and death for centuries. Alone against an army of psychos and demons, Sarah Mandy, an art student who seems to have supernatural abilities of her own, is the only person left to prevent the Mother of Tears from destroying Rome.