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Valparaíso, Chile, 1933. Years of psychiatric treatment and a seemingly happy marriage will not take away Elisa's memory of that youthful love. So, when some years later, Rebecca becomes a beautiful feminist, Elisa's fragile world will collapse in front of her eyes.
Isidora immerses itself, in the manner of a journey through time and space, in the life of Chilean playwright Isidora Aguirre (1919-2011) and in the main ones of her 30 plays, which are recreated on screen by outstanding actors. Mixing family archives, life diaries and interviews she gave at the age of 91, the film becomes the creative biography of the author of La Pergola de las Flores, her most famous work, and opens the door to the social and political issues she narrated in her theater, the utopias that could not be and the conflicts that are still ongoing in Latin America.
Laura returns to Chile, after thirty years, to say goodbye to his old and sick mother. In this bitter journey she is accompanied by his daughter Elizabeth, who still did not know her grandmother. When the old woman meets her granddaughter, she decides to change her will and leave the young Elizabeth as heir of the family mansion. When soon after the grandmother dies, Elizabeth examines the inheritance, and discovers with surprise that the mansion was donated to a foundation.