Wiley Roth finds a severed human finger in his kitchen one night. Understandably freaked out, in a search across Los Angeles that brings them in contact with psychics, ineffectual police, crooked taxidermists, mysterious neighbors who might be on drugs, and a nine-fingered woman named Cheryl who might, improbably, end up being the girl of his dreams.
James Bishop is a young psychology resident, excited about his new job at St. Andrews Mental Hospital and the chance to help severely ill patients. The excitement changes to puzzlement, concern and finally terror as some of those patients mysteriously die and James' efforts to find the cause results in increasingly strange behavior from the St. Andrews staff. Things begin to clarify when James finally encounters the Harvester...
When entertainment lawyer Wolfgang Leighton decides to take a break from business for some fishing in Tennessee's backwoods, he ends up embroiled in a bank robbery and murder. Pursued by the killers, he's running from the police and a young hitchhiker appears to be his only friend.
Theresa is one of the twelve jurors who have to decide about a case of assassination. She believes very strongly in the innocence of the young man, but can't convince the others. During the discussions, she realizes that one member of the jury knows details that he couldn't know from the trial alone. Since no one believes her suspicions, she investigates on her own.
A quartet of murderous psychopaths break out of a mental hospital during a power blackout and lay siege to their doctor's house.