A wealthy banker wants to tear down a tenement slum to build a factory, but a charming girl who lives there begins to persuade him otherwise.
When her cotton crop is burned, Barbara Pelham, a beautiful southern girl, comes to New York to find work as a fashion designer, staying with Mrs. Kemp, a woman she meets on the northbound train. In Mrs. Kemp's house, Barbara encounters Peter Heffner, a wealthy stockbroker, and discovers from him that she has taken up residence in a whorehouse. There is a police raid, but Barbara escapes arrest and returns home. Heffner's son, Neil, goes south to inspect some family property and there meets Barbara, with whom he falls in love. They decide to be married, and she accompanies him to New York, where she meets the elder Heffner for a second time. He denounces her as a whore, but Barbara goes to Mrs. Kemp, who explains the misunderstanding to everyone's satisfaction.
Frank Prentiss, a multi-millionaire who hates and distrusts women, convinces his adopted son, Jack, that they are detrimental to a man's success. The overworked Frank is forced to rest at the country home of his friend, Mr. Gray, where he meets and falls in love with the host's daughter, Kate. She refuses his proposal at first, but later accepts because her father, who has two younger children, is experiencing financial difficulties. Following the wedding, Kate is subjected to Frank's verbal abuse and seeks solace with Jack. Their friendship enrages Frank, who tortures them with his accusations. During a dinner party, Frank accuses Jack and Kate of being lovers in front of the male guests. Jack is restrained from accosting his father, but Frank suffers a fatal heart attack. Later, Jack and Kate fall in love and are married.
Mrs. Emma McChesney is a determined and successful traveling saleswoman for T. A. Buck's Featherbloom Petticoat Company. When Buck dies and his son, T. A. Buck, Jr., takes charge, the company suffers and Emma nearly accepts a job offer from Buck's rival, Abel Fromkin.