A year after college, seven friends Diane Villaruel, Ricky Salveron, Ese Aragon, Joey Fajardo, Gina de Leon, Garry Ballesteros, Melani Suntay, and Brian Lorenzo get together to take a memory down the lane and attempt to relive the past filled with challenges, victories and problems. Things are not anymore as they seemed to be as each of them treads on different path to self-discovery and accomplishment. Gina and Gary are preparing for their wedding when they learn about Gina’s troublesome reproductive system. On the other hand, just when Melanie finally gave her yes to Brian, the latter met an accident and fell in coma. Ese and Joey learned to be sweeter with each other until Joey got his dream car. And lastly, Ricky, who has been long waiting for his Diane lacked the enough courage to confess when Diane came in.
The moment the doctor confirms his wife's pregnancy Carlo felt a sign of a curse coming to life. It's the curse caused by his errant grandfather, the curse that doomed his father. The same curse that's about to destroy him. Advised by his doctor to rest, Carlo returns to his family's villa in Lucban and there, he meets Carmen, the woman destined to kill her.
A 30-year-old widower realizes that his three children need a mother figure. His youngest daughter feels lonely and finds it hard to cope with schooling. He scouts around for a tutor for his daughter, someone who could also act as her playmate and friend. The lady who arrives -- a cheerful singer and tutor -- brings light to their home lives.
Alma and Teresa Carrillo are illigitimate children of Basilio who belongs to a rich clan, but they were never accepted by his mother Josefa and his wife Doreen. The sisters never expected any help from their father despite all their suffering. They suffered more when Alma's husband Teddy was killed, leaving in their care her two sons Abet and Jun. When Alma died, only their half-brother Raffy helps Teresa. Teresa fights back and confronts the Carrillos.
Valerie, a maid of French descent (Monica Seller), comes to work for a family in Saigon of the 1930s/40s. One by one, she seduces the members of the family: the dame de la maison, the widower, young gay sonny with his friend from university, and grandpa.
Cris Cuenca is a poor, oppressed and hard-working family man. He tries to stay out of trouble to be able to provide for his family, but the unkind world drives him into action -- nurturing anger and hatred. Armed with a desert eagle and a talisman that protects him from bullets, Cuenca becomes an assassin and a drug lord