In the near future, a weary Logan cares for an ailing Professor X in a hideout on the Mexican border. But Logan's attempts to hide from the world and his legacy are upended when a young mutant arrives, pursued by dark forces.
Years after a mysterious plague has devastated the planet and turned most of humanity into blood-hungry creatures, a rogue drifter on a vengeful hunt stumbles across a band of survivors in an abandoned police station and reluctantly agrees to try to help them defend themselves and escape to the sanctuary they so desperately need.
The story of two sisters who have been raised in isolation, subjected to the torment of their abusive, drug dealing father. When they finally decide to report him to the police, he kills the two officers and is put in jail. But things go from bad to worse when the girls must answer to their Uncle Costello, a psychotic drug kingpin, who shows up looking for his missing merchandise which is hidden in the woods.