Schoolteacher Bertram Cates is arrested for teaching his students Darwin's theory of evolution. The case receives national attention and one of the newspaper reporters, E.K. Hornbeck, arranges to bring in renowned defense attorney and atheist Henry Drummond to defend Cates. The prosecutor, Matthew Brady is a former presidential candidate, famous evangelist, and old adversary of Drummond.
Mame Dennis, a progressive and independent woman of the 1920s, is left to care for her nephew Patrick after his wealthy father dies. Conflict ensues when the executor of the father's estate objects to the aunt's lifestyle and tries to force her to send Patrick to prep school.
After WW2, a Los Angeles crime ring uses a complex scheme, involving a freight ship, a junkie, and a corrupt health officer, to smuggle drugs into the USA.
New York City newspaper writer J.J. Hunsecker holds considerable sway over public opinion with his Broadway column, but one thing that he can't control is his younger sister, Susan, who is in a relationship with aspiring jazz guitarist Steve Dallas. Hunsecker strongly disapproves of the romance and recruits publicist Sidney Falco to find a way to split the couple, no matter how ruthless the method.
A pair of divorced actors are brought together to participate in a musical version of The Taming of the Shrew. Of course, the couple seem to act a great deal like the characters they play, and they must work together when mistaken identities get them mixed up with the mafia.
Lorelei Lee is a beautiful showgirl engaged to be married to the wealthy Gus Esmond, much to the disapproval of Gus' rich father, Esmond Sr., who thinks that Lorelei is just after his money. When Lorelei goes on a cruise accompanied only by her best friend, Dorothy Shaw, Esmond Sr. hires Ernie Malone, a private detective, to follow her and report any questionable behavior that would disqualify her from the marriage.
An airline pilot pursues a live-in babysitter at his hotel and gradually realizes she is not as stable as perhaps she should be.
Having met on a train, a smooth-talking psychotic socialite shares his theory on how two complete strangers can get away with murder to an amateur tennis player — a theory he plans to test out.
Bart Tare is an ex-Army man who has a lifelong fixation with guns, he meets a kindred spirit in sharpshooter Annie Starr and goes to work at a carnival. After upsetting the carnival owner who lusts after Starr, they both get fired. Soon, on Starr's behest, they embark on a crime spree for cash.
Pinky, a light skinned black woman, returns to her grandmother's house in the South after graduating from a Northern nursing school. Pinky tells her grandmother that she has been "passing" for white while at school in the North. In addition, she has fallen in love with a young white doctor, who knows nothing about her black heritage.
Secret Service agents make a deal with a counterfeiting inmate to be released on early parole if he will help them recover some bogus moneymaking plates, but he plans to double-cross them.
A stranded carnival dancer takes on a corrupt political boss when she marries into small-town society.
Wide-eyed and poor young Leonora weds an obsessive millionaire named Ohlrig, but the marriage is loveless. Even worse, Ohlrig seems to have manic, violent tendencies. Eventually, young Leonora escapes her unhappy life and begins working with New York City doctor Larry Quinada, who she soon falls for. Unfortunately, Ohlrig refuses to grant his wife a divorce, and things get even darker for Leonora when she realizes she's pregnant with his child.
Roy Martin aka Roy Morgan is a burglar and former war-time Radio & Electronics Engineer who listens in to radio police calls, allowing him to stay one step ahead of the cops.
After marrying her long lost love, a pianist finds the relationship threatened by a wealthy composer who is besotted with her.
A gambler discovers an old flame while in Argentina, but she's married to his new boss.
High-school principal Dr. Alfred Carroll relates to an audience of parents that marijuana can have devastating effects on teens: a drug supplier entices several restless teens, Mary and Jimmy Lane, sister and brother, and Bill, Mary's boyfriend, into frequenting a reefer house. Gradually, Bill and Jimmy are drawn into smoking dope, which affects their family lives.
Madcap couple George and Marion Kerby are killed in an automobile accident. They return as ghosts to try and liven up the regimented lifestyle of their friend and bank president, Cosmo Topper. When Topper starts to live it up, it strains relations with his stuffy wife.