The lives of two young families who lived in the same house, starts turning upside down when they find the amulet that La Llorona uses to try to pull her children from the waters and bring them to life. While the authorities investigate what appears to be abused children, the spirit of La Llorona intensifies her attacks on those families.
Saúl Montemayor is suffering loss in drug shipments because he has a snitch in his criminal organization, so he will put a plan in place so that this does not continue to happen and he will use three of his lovers to be able to eliminate whoever gets in the way of his plans.
Pedro Montaño receives a proposal from his friend El Negro to rob the mafia and make easy money. Pedro accepts because he needs the money to cure his wife. This unleashes a war with mobsters like Don Lucio and other criminal organizations that will defend their territories and interests, thus creating the 'New Mafia'.