Asadharan is the story of Jagabandhu, a man who is always eager to help people. He doesn't even think of his well-being in his efforts to do so. The district's magistrate asks him to help him and reveals the corrupt government officials. Jagabandhu falsely declares his death, hoping to get financial help and the support of the people. No one turns up for his funeral, and he is disheartened. He reveals the corrupt people and leaves his district forever.
A disastrous cyclone strands a rich girl and a poor man on a secluded island.
Shipra is a poor woman who is molested and killed as she witnesses corruption. The police and lawyer Somnath take up the case and slowly dig into it. He traces the corrupted policeman and comes to know that Karuna, the head lady of the orphanage where Shipra used to live is equally involved in female trafficking. However, when he sees Karuna his world is turned upside down. Karuna is Shukla, Somnath’s long-lost wife. Circumstances had led her to become a puppet in the hands of the gangsters. However, she is to keep mum about the entire conspiracy, lest they kill her only daughter. Somnath gives assurance to Karuna to speak the truth. She does that and, in the end, the entire gangster network is caught. Karuna’s daughter is proved to be Somnath’s daughter. They get together again.
Siddhartho Chowdhury, a brilliant young medical student, is forced to leave his studies after his father's sudden demise. He is forced to navigate the high unemployment rate and the communist socio-political climate of 1960s Calcutta in search of a job. He lives in a flat with his younger, employed sister, revolutionary brother and widowed mother. The strain of the situation ultimately causes him to hallucinate.