Nerdy high schooler Arnie Cunningham falls for Christine, a rusty 1958 Plymouth Fury, and becomes obsessed with restoring the classic automobile to her former glory. As the car changes, so does Arnie, whose newfound confidence turns to arrogance behind the wheel of his exotic beauty. Arnie's girlfriend Leigh and best friend Dennis reach out to him, only to be met by a Fury like no other.
A young woman with precognition realizes she is being stalked by a killer -- a mass murderer she previously had used her psychic powers to identify to the skeptical police.
John, a disillusioned Vietnam War journalist, turns to heroin smuggling. He cons Ray, an equally burnt out veteran into delivering the drugs stateside to his wife. Everything soon falls apart and Ray ends up on the run with John's wife trying to evade crooked narcotics agents.
Ken loves to design and build exotic cars. When the High School shop class project car, a fully tricked out dream Corvette, is stolen, he begins searching for it. His search leads him to Las Vegas, where Vanessa, a teenaged prostitute wannabe, helps him try to track it down.
A housewife flees from a policeman's killer on the road between Phoenix and Denver.
When virtually all of the residents of Piedmont, New Mexico, are found dead after the return to Earth of a space satellite, the head of the US Air Force's Project Scoop declares an emergency. A group of eminent scientists led by Dr. Jeremy Stone scramble to a secure laboratory and try to first isolate the life form while determining why two people from Piedmont - an old alcoholic and a six-month-old baby - survived. The scientists methodically study the alien life form unaware that it has already mutated and presents a far greater danger in the lab, which is equipped with a nuclear self-destruct device designed to prevent the escape of dangerous biological agents.
While passing through the town of Bannock, a bunch of drunken cattlemen go overboard with their celebrating and accidentally kill an old man with a stray shot. They return home to Sabbath unaware of his death. Bannock lawman Jered Maddox later arrives there to arrest everyone involved on a charge of murder. Sabbath is run by land baron Vince Bronson, a benevolent despot, who, upon hearing of the death, offers restitution for the incident.
Cathy Timberlake is en route to a job interview when a car transporting businessman Philip Shayne covers her in mud. He sends his assistant, Roger, to apologize, but upon meeting Cathy, Roger knows that she would be a suitable match for his boss. Despite their mutual attraction, Cathy and Philip want different things. Philip wants a fling, while Cathy wants a marriage. As they travel to exotic locales, their differing motivations are put to the test.