A prison bus with over a dozen criminals on board has an accident and rams another car, in which Dr. Douglas Madsen was on his way home. Most of the prisoners die. Four of them survive, one of them severely injured. After having killed all the guards, they head for the woods. They take Dr. Douglas Madsen hostage. Suddenly a huge house appears in the middle of the woods. The leader of the group, Arthur, emphasizes that he will kill Douglas and every single member of the "family" if his wounded brother would die. Meanwhile some members of the family show strange behavior, and very soon mayhem breaks loose.
David Glover is a young, American man who is working as a courier at his uncle's company, "Berling Express". David is attracted to a female co-worker by the name of Jenny, who also happens to have feelings for him. During one of his courier jobs, the attractive Lara, who claims to be a policewoman, jumps into his car and David finds himself in an exchange of fire. David is willing to help Lara, but soon finds himself framed as the professional assassin LORCA. Now David must run from the police and catch the real LORCA, who is hell-bent on murdering the last surviving witness to a brutal murder.
Editor Eckernförde has come into the possession of an audiocassette that contains a recording of the last minutes of deceased politician Uwe Barschel. The circumstances of his untimely death have never been completely resolved - until now. Unfortunately, the editor's daughter Nina accidentally takes the tape with her to Munich, where she is about to visit her paralyzed Mom in a sanatorium. When this information reaches the CIA and the BND, both organizations compete to get hold of the tape. Meanwhile Erkan & Stefan, two loveable wannabe supercheckers from Munich, are assigned as bodyguards for Nina - of course, they are expected to mess up their job, so that the tape can be retrieved. But the two friends prove to be a bit more streetwise than CIA or BND ever expected.