Loosely based on real events that took place during Matteo Messina Denaro's thirty years on the run. A disgraced politician is gifted a second chance when secret services involve him in an operation to root out an elusive Mafia boss. Using his personal connection as the Boss' godfather, his task is to get him to reveal his hiding place in their secret letters.
These are the years of the First World War and Dr. Stefano Zorzi spends his days in the Exemption Clinic in a large city of Northern Italy, where he not only takes care of soldiers who arrive from the massacre of the front, but also he fights simulation and self-harm of those who hope to be dispensed, by sending them before the Military Court. If Stefano, in fact, does his utmost to heal soldiers and send them back to fight, Dr. Giulio Farradio makes them ill, or helps them to self-injure seriously enough to be exonerated. The two doctors, who went to university together and were great friends, they not only (secretly) challenge each other on a professional level, but also on the sentimental one: they are both linked to Anna, a courageous nurse with a strong character. But when the great ‘Spanish’ fever epidemic arrived in 1918, the time for love, politics and science ends up getting confused dangerously...
Federico celebrates his birthday in the mountains with his historical group of old friends. Despite the affection and memories of so many years spent together, Federico's mind is clouded by some doubts and uncertainties, which lead him to reflect on his relationships and on himself.