As a wealthy retired surgeon nears the end of his life, he begins to distribute his wealth to those in need, stating that "all that I have belongs to God." His nephews bring him to court to determine his mental competence in the hopes of stopping him from disposing of all his money.
A holiday favourite for generations... George Bailey has spent his entire life giving to the people of Bedford Falls. All that prevents rich skinflint Mr. Potter from taking over the entire town is George's modest building and loan company. But on Christmas Eve the business's $8,000 is lost and George's troubles begin.
After a demonstration of new PT boats, navy brass are still unconvinced of their viability in combat, leaving Lt. "Rusty" Ryan frustrated. After the attack on Pearl Harbor, however, Ryan and his buddy Lt. Brickley are told they can finally take their squadron into battle. The PT boats quickly prove their worth, successfully shooting down Japanese planes, relaying messages between islands, and picking off a multitude of enemy ships.
Anita, engaged to solid Don Barnes, is swept off her feet by magician Arturo. Before you can say presto, she's his wife and stage assistant on a lengthy world tour. But Anita is annoyed by Arturo's constant flirtations, and his death-defying stunts give her nightmares. And forget her plan to retire to a farmhouse. Eventually, she has had enough and disappears.
Falling in love with the voice of Broadway chanteuse Margaret Garret, cocksure young tycoon Daniel Brewster decides to rescue the star from her hectic lifestyle of frenzied fans and mooching relatives. When Margaret has her ardent suitor arrested, the judge appoints her as Daniel's probation officer, forcing the duo to spend time together. As Daniel teaches Margaret to let her hair down and enjoy life, she begins to fall for her fun-loving admirer.
In the 1840s, Ramsey MacKay, the driver for the struggling Wells Fargo mail and freight company, will secure an important contract if he delivers fresh oysters to Buffalo from New York City. When he rescues Justine Pryor and her mother, who are stranded in a broken wagon on his route, he doesn't let them slow him down and gives the ladies an exhilirating ride into Buffalo. He arrives in time to obtain the contract and is then sent by company president Henry Wells to St. Louis to establish a branch office.
When a major newspaper accuses wealthy socialite Connie Allenbury of being a home-wrecker, and she files a multi-million-dollar libel lawsuit, the publication's frazzled head editor, Warren Haggerty, must find a way to turn the tables on her. Soon Haggerty's harried fiancée, Gladys Benton, and his dashing friend Bill Chandler are in on a scheme that aims to discredit Connie, with amusing and unexpected results.
With a full Hollywood background and settings but more an expose of scandal-and-gossip magazines of the era, has-been actor John Blakeford agrees to write his memoirs for magazine-publisher Jordan Winston. When Blakeford's daughter, Patricia, ask him to desist for the sake of his ex-wife, Carlotta Blakeford, he attempts to break his contract with Winston.
Richard, a millionaire in love with his secretary, Diane, is dispirited when his wife refuses to divorce him. Concerned that Diane will now lose interest, Richard offers her an all-expense-paid cruise to Argentina so that she can think it over. While traveling, however, Diane falls in love with fellow traveler Mike. She resolves to come clean to Richard, but upon return she becomes conflicted when she finds out he was able to get divorced after all.
American Civil War, 1862. After the disaster of the Second Battle of Bull Run, Major Allen, chief of the Secret Service of the Union, asks actress Gail Loveless to become one of his operators and infiltrate enemy territory.
Among the travelers of varied backgrounds that meet and interact on one night at Union Depot, a metropolitan train station, are Chick and his friend Scrap Iron, both newly released from prison after serving time for vagrancy. Hungry and desperate for a break, Chick fortuitously comes across across a valise abandoned by a drunken traveler. In it he finds a shaving kit and a suit of clothes with a bankroll, which help transform the affable tramp into a dashing gent. After buying himself a meal, Chick seeks some female companionship among the many hustlers who walk the station. He propositions Ruth Collins, a stranded, out-of-work showgirl and takes her to the station's hotel.
After a tumultuous first marriage, Millie Blake learns to love her newfound independence and drags her feet on the possibility of remarriage. The years pass, and now Millie's daughter garners the attentions of men - men who once devoted their time to her mother.