Mingo and Aníbal are two friends who work at a car dealership and are accused of a murder they did not commit. The incident occurred in a remote house, where both friends go to try to hide and solve the crime. There they will try to elude a ghost that wanders in the place while trying to regain their innocence.
Friends Alberto and Jorge, who work together in an insurance company and live in the same building, are married to two sisters (Elsa and Alicia). When they go on vacation to Mar del Plata, Alberto and Jorge decide to enjoy their "single life". In addition to this, they have to fulfill a duty entrusted by their boss: to find the revue theater entrepreneur Félix Sagastume, to sign an insurance contract. It is in a canteen where they go to look for him, and there they meet two aspiring vedettes (Zuzú and Bibí), who confuse them with important businessmen and see in them a possibility of achieving fame.
Friends Alberto and Jorge, who work together and live in the same building, are married to two sisters (Ethel and Gogó). Noticing that their sex life becomes boring, they cheat on them with co-workers. This is discovered and they are fired. Then, they get employed in a beauty institute, where they have many women at their disposal. Their wives learn of this mischief, and go to look for them at the institute, generating hilarious situations.
Marisol is a girl of 16 who, accompanied by her father, is singing from place to place, to put food in their mouths. They end up going to a camp site in Mallorca, where the girl meets two students from Madrid, Tony and Mario. Marisol wants to become someone great, and to achieve that, she performs at a bullfighting tournament as a singer, in the hope that someone will see her. Mr. Morrison and Miss Nelly notice her. This man puts his expectations in Marisol, but to do that, he takes her away from the environment she has lived in until then. That way, he will get the world to consider her "a lady with great talent" (her voice), which is what she wanted in the first place.
While on tour through Latin America, los Grandes del Buen Humor are confused with volunteers for a space travel and get tangled with spies.