Opportunist and liar, Joseph Watkins, puts on a play at a theatre with a murderous past to impress, Virginia, an actor on the verge of leaving town. While evading two detectives and to the alarm of his stage manager, Joseph becomes obsessed with the spirit of the theatre and begins killing those who get in his way.
An artist, Chance finds the perfect muse, Charlie, for his work. Despite the best efforts of his girlfriend Lily and his mentor Marius, Chance blurs the line between inspiration and obsession and twists his way through Charlie's life. When Chance sees that Charlie has a boyfriend, Michael, he realizes that in order to achieve inspiration sacrifices must be made.
The greedy Braylon owns the Just Rite Sugar Company and has hired the unethical scientist Sergei to conduct an experiment to make an addictive sugar stronger than heroin or nicotine to increase his sales. Sergei uses invisible people as test subjects, like beggars, addicted junkies and illegals, in the clandestine Shadow Rock Mill. When Braylon's men mistakenly kidnap Ryan, who is the brother of his secretary Erin and son of his security chief Griff, and Hannah, the youngster becomes an important non-contaminated subject. However, Erin receives some mysterious e-mails from the unknown Cinderella with a picture of Ryan and a hint that he might be in Shadow Rock and together with her father, they decide to seek out Ryan.
In the countryside, the boy Alan and his friend Becky steal a creepy wooden box with a powerful voodoo stick inside from his voodooistic neighbor. When the boy draws with the stick, his drunken father is attacked by a snake and vanishes. Years later, Alan and Becky are married to each other; while planting some flowers to celebrate the death of Alan's mother, Becky finds the box buried in the garden and she keeps the stick in her pocket. Meanwhile, five friends are traveling in a monster truck, drinking beer. The driver accidentally runs over Becky, but believes he had hit an animal. When Alan witnesses the hit-and-run and sees his wife dead, he uses the stick seeking revenge against the youngsters.