Alexander's day begins with gum stuck in his hair, followed by more calamities. Though he finds little sympathy from his family and begins to wonder if bad things only happen to him, his mom, dad, brother, and sister all find themselves living through their own terrible, horrible, no good, very bad day.
Behrani, an Iranian immigrant buys a California bungalow, thinking he can fix it up, sell it again, and make enough money to send his son to college. However, the house is the legal property of former drug addict Kathy. After losing the house in an unfair legal dispute with the county, she is left with nowhere to go. Wanting her house back, she hires a lawyer and befriends a police officer. Neither Kathy nor Behrani have broken the law, so they find themselves involved in a difficult moral dilemma.
Multi-platinum rap superstars Redman and Method Man star as Jamal and Silas, two regular guys who smoke something magical, ace their college entrance exams and wind up at Harvard. Ivy League ways are strange but Silas and Jamal take it in a stride -- until their supply of supernatural smoke runs dry. That's when they have to start living by their wits and rely on their natural resources to make the grade.
When Claire Spencer starts hearing ghostly voices and seeing spooky images, she wonders if an otherworldly spirit is trying to contact her. All the while, her husband tries to reassure her by telling her it's all in her head. But as Claire investigates, she discovers that the man she loves might know more than he's letting on.