A research scientist becomes the world's first pregnant man in order to test a drug he and a colleague have designed for expectant women. To carry out the trial, he has an embryo implant, believing that he will only carry the baby for three months – hardly expecting to face the prospect of giving birth.
Brash and gutsy stripper Bettina and mousy secretary Jeannie are framed for a murder they didn't commit. The radically contrasting distaff duo go on the lam in a red convertible with a half million dollars in cash in a briefcase. Various folks on both sides of the law give hot pursuit.
Lukas Armand, a skull-faced movie producer, is auditioning lovely young starlets for his upcoming low-budget horror pic. The girls are delighted to learn they've been chosen to star in the film until Lukas' creepy gofers; Jason and Mad-dog kidnap the actresses, one by one and lock the terrified girls somewhere in the bowels of the film studio.
Two sisters in the Vice Academy try to thwart the crime wave wrought by escaped convict Malathion, who got her name after being exposed to toxic chemicals. An honest new recruit does such a good job at arresting Malathion's gang that the sisters are taken off active duty. To get their jobs back, they try to tarnish the new girl's reputation.
The comic strip detective finds his life vastly complicated when Breathless Mahoney makes advances towards him while he is trying to battle Big Boy Caprice's united mob.