On the outskirts of town, the hard-nosed Vienna owns a saloon frequented by the undesirables of the region, including Dancin' Kid and his gang. Another patron of Vienna's establishment is Johnny Guitar, a former gunslinger and her lover. When a heist is pulled in town that results in a man's death, Emma Small, Vienna's rival, rallies the townsfolk to take revenge on Vienna's saloon – even without proof of her wrongdoing.
Six wanted outlaws are rounded up and captured by the Cheyenne Kid. Collecting the reward money, Cheyenne instructs his sidekick Fuzzy Q. Jones to give the money to a group of financially strapped ranchers. Alas, Fuzzy falls off his horse, loses his memory, and forgets what became of the money.