Oscar has dedicated his life to the well-being of his disabled son, Billy. When Oscar is diagnosed with cancer, he forges a plan to train his son the intricacies of bagging groceries in the hopes of landing Billy his first job and beginning a life of independence.
Decades since their successful television series was canceled, Chip has succumbed to a life of suburban domesticity as an insurance salesman. Dale, meanwhile, has had CGI surgery and works the nostalgia convention circuit, desperate to relive his glory days. When a former cast mate mysteriously disappears, Chip and Dale must repair their broken friendship and take on their Rescue Rangers detective personas once again to save their friend’s life.