Unlucky assassin Ladybug is determined to do his job peacefully after one too many gigs gone off the rails. Fate, however, may have other plans, as Ladybug's latest mission puts him on a collision course with lethal adversaries from around the globe—all with connected, yet conflicting, objectives—on the world's fastest train.
In the Susukino red light district of Sapporo, a private detective (Yo Oizumi) drinks alcohol with his driver Takada (Ryuhei Matsuda) in his favourite bar. There he receives a phone call from a woman who identifies herself as Kyoko Kondo. The woman asks the detective to complete a simple task. The detective, having an excellent sense for danger, thinks the work is easy and accepts the case. The next day he begins the investigation.