Set in the sordid underworld of drug trafficking and prostitutes, this story involves Charlie Smith, private eye, whose job it is to find Carrie Friskine and fast! Carrie, a cat burglar, has ripped off the ring-leader of a drug racket and now he's after her blood.
Owen Legate, a railroad official, comes to Dodson, Mississippi to shut down the local railway - the town's main income. But Owen unexpectedly finds love with Dodson's flirt and main attraction, Alva Starr.
A group of unlikely travelling companions find themselves on the same stagecoach to Cheyenne. They include a drunken doctor, a bar girl who's been thrown out of town, a professional gambler, a travelling liquor salesman, a banker who has decided to embezzle money, a gun-slinger out for revenge and a young woman going to join her army captain husband. All have secrets but when they are set upon by an Indian war party and then a family of outlaws, they find they must all work together if they are to stay alive.