The ultimate disaster film parody. A nuclear-powered bus is making its maiden non-stop trip from New York to Denver. The journey is plagued by disasters due to the machinations of a mysterious group allied with the oil lobby. Will the down-on-his-luck driver, with a reputation for eating his passengers, be able to complete the journey?
A dishonest businessman asks rich layabout Craig Blake to help him buy a gym, which will be demolished for a development project in Alabama. But after spending time with weightlifter Joe Santo and gym worker Mary Tate Farnsworth, Craig wants out of the deal. The property negotiations turn ugly, causing a brawl at the gym and a spectacle at a big bodybuilding meet, as Craig learns that it's not easy to turn your back on fair-weather friends.