Routine brain surgery makes a terrifying turn when a tumor goes rogue and takes on a life of its own. It runs amok in search of its next meal.
Will Spanner, the reluctant heir to a dark legacy, is again thrown into battle against the forces of evil when a series of gruesome murders begins to take place. The victims are all brutally murdered in a ritualistic fashion - the heart is taken from each corpses. The victims also have something else in common with Will, something that the minions of darkness will stop at nothing to possess.
A deranged female serial killer stalks seven young people whom phone a radio call-in show to discuss their darkest fears and a night-long game of cat-and-mouse is put into motion by the darkly sinister-looking murderess.